Enantiomeric Resolution of Five Chiral Pesticides on a Chiralpak IB-H Column by SFC

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Reversed-Phase UHPLC Enantiomeric Separation of Rasagiline Salts Using a Chiralpak® AGP Column

We report the first rapid ultra-high performance liquid chromatographic (UHPLC) enantiomeric reversed-phase separation of rasagiline mesylate and its tartrate salts using a Chiralpak® AGP column (50 mm × 2.1 mm, 5 μm) as a stationary phase. This method was developed as an alternative to the usage of previously reported normal-phase chiral LC columns for isomer separation. Our method is based on...

متن کامل

Enantiomer separation of non - steroidal anti - infl ammatory drugs Using Daicel immobilized polysaccharide - derived chiral columns and the Agilent 1260 Infi nity Analytical SFC System Application

The enantiomer separation by supercritical fl uid chromatography (SFC) of six profen drugs was investigated on the new generation of chiral columns from Daicel Corporation, that are packed with the immobilized polysaccharide-derived chiral stationary phases CHIRALPAK IA, CHIRALPAK IB, CHIRALPAK IC, and CHIRALPAK ID. Methanol, ethanol, 2-propanol and acetonitrile were used in combination with tr...

متن کامل

Determination of Enantiomeric Excess of Metolachlor from Chiral Synthesis using the Agilent 1260 Infi nity Analytical SFC System

This Application Note describes the development of a method for the separation of four stereoisomers, which were derived from a compound with two steric centers. The method was developed using an Agilent 1260 Infi nity Analytical Supercritical Fluid Chromatography (SFC) solution with Agilent ChemStation Method Scouting Wizard software. The developed method was used to compare the ratio of stere...

متن کامل

Chiral Analysis of Pesticides and Drugs of Environmental Concern: Biodegradation and Enantiomeric Fraction

The importance of stereochemistry for medicinal chemistry and pharmacology is well recognized and the dissimilar behavior of enantiomers is fully documented. Regarding the environment, the significance is equivalent since enantiomers of chiral organic pollutants can also differ in biodegradation processes and fate, as well as in ecotoxicity. This review comprises designed biodegradation studies...

متن کامل

Enantiomeric Separation of Rivaroxaban by a Chiral Liquid Chromatographic Method

Methods: An enantioselective reversed phase high performance liquid chromatographic method was developed and validated. The enantiomers of rivaroxaban was resolved on a Chiralcel OD-H (250 mm × 4.6 mm, 5 mm) column using a mobile phase system containing n-hexane –isopropanol (50: 50 v/v/) and column temperature at 35°C. The resolution between the enantiomers was not less than 2.0. The developed...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Chromatographic Science

سال: 2011

ISSN: 0021-9665,1945-239X

DOI: 10.1093/chrsci/49.9.739